|
|
|
|
|
Click Here to return To Results
|
|
|
|
Correlation between the clinical status and the MRI findings on admission was poor.Of 20 patients with clinically advanced disease,only 8 had marked MR abnormalities;6 had normal or almost normal findings on MR examinations.Two of 4 patients with clinically mild disease had advanced MR changes.The progression of the MR findings appeared to follow a constant pattern.The earliest pathologic finding was focal,high T2- intensity white matter changes;lateral atrophic changes followed.The atrophy lagged behind the white matter changes and was thus mild when white matter changes were moderate or severe.In the most advanced stage, when the patient was in a neurovegetative state,an almost total loss of white matter had usually taken place.At this stage,the corpus callosum was also thin.Basal ganglia changes,usually involving the putamina,were seen in one third of patients and cortical gray matter changes were seen in one fourth of patients examined with MR imaging.In 2 of 20 patients,MR changes regressed in parallel with clinical improvement following therapy,but in 5 patients,clinical improvement was accompanied by progression of MR changes.The progress of MR abnormalities seen in patients with SSPE seems to follow a constant pattern,but the severity of MR changes does not always correlate well with the clinical findings.Caution must therefore be used when evaluating the effects of therapy. |
|
(click to filter results - removes previous filter)
basal ganglia,lesion of
CAT scan
CAT scan,abnormal
CAT scan,contrast enhanced
CAT scan,false negative
encephalitis
lenticular nucleus,lesion of
lenticular nucleus,lesion of,bilateral
MRI
MRI,abnormal
MRI,CAT scan compared to
prognosis
review article
subacute sclerosing panencephalitis(S.S.P.E.)Dawson's disease
white matter disease
|
Click Here to return To Results
|
|